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. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Int J Parasitol. 2008 Aug 12;39(3):315–326. doi: 10.1016/j.ijpara.2008.07.007

Fig. 3.

Fig. 3

Effect of PF1 on voltage-activated currents. (A) Representative traces showing voltage-activated currents in control, during PF1 (1 μM) application and post-wash. Two currents observed outward potassium currents (O) and transient inward calcium current (Ipeak). Note the increase in the plateau of outward current and the decrease in the Ipeak current. (APF-Ringer no calcium or potassium channel block). (B) Current–voltage plot of the mean potassium current before, during and after PF1 (1 μM) application. Control: Inline graphic PF1 (1 μM): Inline graphic Post-wash: Inline graphic (C) Current–voltage plot of the calcium transient inward current (I) before, during and after PF1 (1 μM) application. Control: Inline graphic PF1 (1 μM): Inline graphic Post-wash: Inline graphic (D) Long-lasting potentiation of the mean (O) potassium current before, during and after PF1 (1 μM) application (paired t-test, n = 6, **P ≤ 0.01, *P ≤ 0.05). (E) Inhibition of the peak calcium transient inward current (Ipeak) before, during and after PF1 (1 μM) application (paired t-test, n = 6, **P ≤ 0.01, *P ≤ 0.05).