Table 2.

In vivo biodistribution of [¹⁸F](+)4 in control Sprague-Dawley rats (%ID/g, avg ± SD). For comparison, the biodistribution data of [¹⁸F](+)2 in rats reported previously [28] were added.

Biodistribution of [¹⁸F](+)4 in rats
	2min n=3		30min n=3		60min n=7		120min n=7		240min n=4

Blood	0.27	± 0.05	0.15	± 0.01	0.10	± 0.01	0.04	± 0.00	0.02	± 0.00
Heart	0.48	± 0.09	0.11	± 0.02	0.07	± 0.01	0.02	± 0.00	0.01	± 0.00
Muscle	1.00	± 0.01	0.61	± 0.01	0.04	± 0.01	0.02	± 0.00	0.01	± 0.00
Lung	0.79	± 0.04	0.48	± 0.15	0.14	± 0.04	0.05	± 0.01	0.03	± 0.00
Kidney	4.60	± 1.10	3.59	± 0.80	2.21	± 0.53	1.58	± 0.17	2.01	± 0.30
Pancreas	1.64	± 0.48	1.96	± 0.19	2.68	± 0.28	1.33	± 0.30	0.81	± 0.16
Spleen	1.36	± 0.48	0.26	± 0.05	0.16	± 0.04	0.08	± 0.01	0.04	± 0.01
Liver	3.28	± 0.49	1.02	± 0.12	0.67	± 0.10	0.54	± 0.06	0.54	± 0.11
Skin	0.21	± 0.05	0.14	± 0.01	0.09	± 0.01	0.04	± 0.01	0.02	± 0.01
Brain	0.95	± 0.30	0.30	± 0.01	0.32	± 0.06	0.24	± 0.03	0.28	± 0.04
Bone	0.29	± 0.04	n/a	n/a	0.23	± 0.03	0.22	± 0.04	0.27	± 0.05

Biodistribution of [¹⁸F](+)2 in rats (%ID/g, avg ± SD) reported previously [28]
	2min	30min	60min	120min

Blood	0.26 ± 0.03	0.23 ± 0.06	0.18 ± 0.02	0.12 ± 0.03
Heart	0.71 ± 0.07	0.41 ± 0.03	0.30 ± 0.10	0.22 ± 0.01
Muscle	0.14 ± 0.03	0.17 ± 0.02	0.13 ± 0.01	0.10 ± 0.01
Lung	0.94 ± 0.04	0.69 ± 0.03	0.54 ± 0.14	0.35 ± 0.03
Kidney	2.10 ± 0.17	1.06 ± 0.06	0.84 ± 0.09	0.55 ± 0.06
Pancreas	2.51 ± 0.22	5.50 ± 0.97	4.98 ± 0.24	2.76 ± 0.61
Spleen	1.46 ± 0.15	1.03 ± 0.18	0.83 ± 0.18	0.48 ± 0.04
Liver	3.53 ± 0.56	2.82 ± 0.24	2.47 ± 0.30	1.47 ± 0.13
Skin	0.23 ± 0.05	0.28 ± 0.01	0.23 ± 0.04	0.16 ± 0.02
Brain	0.71 ± 0.05	0.62 ± 0.08	0.42 ± 0.04	0.35 ± 0.02