Skip to main content
. Author manuscript; available in PMC: 2009 Jan 29.
Published in final edited form as: Mol Ther. 2008 May 20;16(7):1252–1260. doi: 10.1038/mt.2008.100

Figure 2. Physical characterization of chimeric-1829.

Figure 2

(a) Primary structure of novel adeno-associated virus (AAV) variant selected from CS1cell. (b) Three-dimensional model showing VP3 subunits of AAV1829 in relation to the fivefold (white pentagon); threefold (white triangle) and twofold (white oval) axes of symmetry. AAV1-derived residues are colored salmon, AAV2 in blue, AAV8 in dark pink, and AAV9 in yellow. (c) Black box region in 2. Panel b shown at higher magnification. Key residues in the C-terminal AAV9 region that differ from AAV2 are colored gray (706); cyan (709); orange (712); green (714); white (716); and black (718) using Vp1 numbering. (d) Heparin binding profiles of AAV1829 and AAV2. L, load; FT, flow through; W, wash; e, elution.