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. Author manuscript; available in PMC: 2009 Jan 29.
Published in final edited form as: Mol Ther. 2008 May 20;16(7):1252–1260. doi: 10.1038/mt.2008.100

Figure 3. Biological characterization of chimeric-1829 compared with some parental serotypes.

Figure 3

(a) Fluorescence micrographs of green fluorescent protein (GFP) transgene expression in CS1 cells transduced with AAV serotypes 1–9 (except 7) and the novel variant chimeric-1829 at a multiplicity of infection (MOI) of 1,000 for 48 hours. (b) Representative fluorescence micrographs of GFP transgene expression in different human and mouse melanoma cell lines infected with chimeric-1829 and parental serotypes at an MOI of 1,000 for 48 hours. (c) Heparin-inhibition assay. Top panels show CS1 cells, and bottom panels show 293 cells. Left and right columns are transduction profiles in the absence and presence of heparin, respectively.