. Author manuscript; available in PMC: 2009 Jan 29.

Published in final edited form as: Am J Epidemiol. 2007 Sep 6;166(12):1400–1408. doi: 10.1093/aje/kwm220

TABLE 4.

Interaction between ALAD^* genotype and patella lead^† in association with prevalent abnormal responses on mood dimension scores, VA Normative Aging Study, United States, 1991–2002

Mood dimension score^‡	ALAD 1-1 (n = 589)		ALAD 1-2/2-2 (n = 119)		p_interaction
Mood dimension score^‡	OR	95% CI	OR	95% CI	p_interaction
Anxiety	1.23	1.02, 1.48	0.97	0.60, 1.56	0.30
Depression	1.09	0.89, 1.34	1.14	0.69, 1.87	0.68
Hostility	1.19	0.98, 1.46	1.26	0.71, 2.24	0.61
Phobic anxiety	1.31	1.04, 1.65	0.79	0.48, 1.29	0.01
Somatization	1.09	0.88, 1.36	1.20	0.76, 1.90	0.46
Global Severity Index	1.25	1.03, 1.52	1.21	0.71, 2.08	0.84
Positive Symptom Total	1.13	0.92, 1.39	1.00	0.63, 1.59	0.59
Positive Symptom Distress Index	1.05	0.87, 1.27	1.27	0.76, 2.14	0.26

ALAD, δ-aminolevulinic acid dehydratase.

^†

Reported are odds ratios (ORs) and 95% confidence intervals (CIs) corresponding to an interquartile increment in patella lead (20 µg/g).

^‡

All analyses were adjusted for age at bone scan, alcohol consumption (categorical), education (categorical), time between Brief Symptom Inventory assessments, and cumulative smoking (pack-years).