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Progressive appearance of CNA motifs exclusive to CWD-infected elk, at least 3 months before clinical signs, and delayed in the CWD-resistant genotype (LM)
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Motif A contains an EVI1 protein binding site. Motif B contains a PLZF binding site. EVI1 is a known promoter for PLZF. Motif C, which appears at the terminal stage in infected animals, has no known function.
