Table 1.
Statistics on over-represented motifs
| Genes | Motifs |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| All | Similar to known TFBS |
Similar to myeloid TFBS |
Non-uniform (NU) |
Occurring in highly correlated subgroup of genes (HC) |
NU and HC |
|||||||
| N | N | N | Percentage | N | Percentage | N | Percentage | N | Percentage | N | Percentage | |
| Gene sets (59 out of 72) | ||||||||||||
| Total | 1532.0 | 5325.0 | 1009.0 | 187.0 | 1772.0 | 1881.0 | 578.0 | |||||
| Average | 26.0 | 90.3 | 17.1 | 18.9 | 3.2 | 3.5 | 30.0 | 33.3 | 31.9 | 35.3 | 9.8 | 10.9 |
| CEG (32 out of 44) | ||||||||||||
| Total | 967.0 | 1943.0 | 367.0 | 70.0 | 651.0 | 645.0 | 210.0 | |||||
| Average | 30.2 | 60.7 | 11.5 | 18.9 | 2.2 | 3.6 | 20.3 | 33.5 | 20.2 | 33.2 | 6.6 | 10.8 |
| CER (25 out of 26) | ||||||||||||
| Total | 390.0 | 3369.0 | 637.0 | 117.0 | 1109.0 | 1227.0 | 359.0 | |||||
| Average | 15.6 | 134.8 | 49.0 | 36.4 | 4.7 | 3.5 | 85.3 | 63.3 | 94.4 | 70.0 | 27.6 | 20.5 |
| CEMR (2 out of 2) | ||||||||||||
| Total | 175.0 | 13.0 | 5.0 | 0.0 | 12.0 | 9.0 | 9.0 | |||||
| Average | 87.5 | 6.5 | 2.5 | 38.5 | 0.0 | 0.0 | 6.0 | 92.3 | 4.5 | 69.2 | 4.5 | 69.2 |
The table reports information on the over-represented motifs that where found in the whole set of selected gene sets and in the three distinct types of gene sets (CEG, CER and CEMR). Reported mean values are calculated only considering those gene sets with over-represented motifs: the number of gene sets with over-represented motifs is shown in the first column, together with the total number of gene sets for each group. Then for each group of gene sets, statistics on the total number of genes are shown along with statistics on the total number of over-represented motifs (All), as well as with statistics on the number of over-represented motifs matching specific characteristics: including motifs matching known TFBS (known TFBS), including motifs matching known TFBS with a known role in myelopoiesis, motifs with non-uniform distribution along the promoters (non-uniform), motifs occurring in a subgroup of highly correlated genes and motifs satisfying the latter two characteristics.