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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Magn Reson Med. 2009 Jan;61(1):22–27. doi: 10.1002/mrm.21827

Figure 1.

Figure 1

MT-weighted images taken at the level of C2 as a function of offset frequency. Panel A: Healthy control. Excellent discrimination between gray and white matter can be appreciated at all offsets greater than 4 kHz. The contrast is such that tissue with a large MT effect (e.g. white matter) is dark relative to GM and CSF (brightest). The image on the bottom right reflects the placement of ROIs used for qMT analysis: lateral columns (red), dorsal column (blue) white matter, and dorso-lateral horn (yellow) gray matter. Panel B: Mildly affected AMN male. At all offsets greater than 1 kHz, tissue hyperintensity in the dorsal column (red arrow) is observed. It should be noted that the dorsal column is the principle site of pathology (ref) in the cervical level of AMN patients.