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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Prog Retin Eye Res. 2008 Apr 6;27(4):450–463. doi: 10.1016/j.preteyeres.2008.03.003

Fig. 1. Summary of the effects of cGMP on holding current in two studies of ON bipolar cells.

Fig. 1

(A) Recording of a tiger salamander ON bipolar cell dialyzed with a solution containing 1 mM cGMP. Note the development of a standing inward current which can be suppressed by application of glutamate. Modified from (Nawy and Jahr, 1990a). (B) Recording from an ON bipolar cell in dogfish retina. The cell was recorded with a pipet solution containing 200 µM cGMP. Note again the development of a standing inward current. Upward deflections are responses to 2 mV voltage steps, used to monitor changes in input resistance. Modified from (Shiells and Falk, 1990). See text for details.