Table 1.
Identity and structure of genes within BACs
| BAC | Ambystoma Sequence | Presumptive Human Ortholog |
Complete Axolotl ORF? |
Introns Identified |
Exons Identified |
| H3_1D2 | Tig_NM_4343_Contig_1 | NP_004334.1 calreticulin precursor | Complete | 8 | 9 |
| H3_4A11 | Mex_Nohits_2574_Contig_1 | Unknown | Complete | 9c | 10 |
| H3_4F24 | Tig_NM_362_Contig_1 | NP_003247.1 tissue inhibitor of metalloproteinase 4 precursor | Unknown | 1c | 3e |
| H3_37I11 | Tig_NM_7006_Contig_1 | NP_008937.1 cleavage and polyadenylation specific factor 5 | Partial | 5 | 6 |
| H3_37I23 | Tig_NM_18948_Contig_1 | NP_061821.1 mitogen-inducible gene 6 protein | Completea | - | 1 |
| H3_37N9 | Mex_Nohits_697_Contig_1 | NP_071436.1 platelet receptor Gi24 | Partial | 5 | 5 |
| H3_41L21 | Mex_NM_687_Contig_1 | NP_000678.1 S-adenosylhomocysteine hydrolase | Pseudogeneb | - | - |
| H3_46H10 | Tig_NM_1428_Contig_1 | NP_001419.1 enolase 1 | Partial | - | 1 |
| H3_48F8 | Tig_NM_859_Contig_1 | NP_000850.1 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | Complete | 14 | 15 |
| H3_48K23 | Mex_NM_20169_Contig_4 | NP_996846.1 retinoic acid receptor responder | Partial | 1c | 2 |
| H3_61C19 | Mex_Nohits_221_Contig_2 | Unknown | Complete | - | 1 |
| H3_61K9 | Mex_NM_5032_Contig_2 | NP_005023.2 plastin 3 | Partial | 1 | 2 |
| H3_62O21 | Mex_NM_18947_Contig_1f | NP_002550.2 purinergic receptor P2X3 | Partial | 7 | 8 |
| H3_67L15 | Tig_NM_4343_Contig_1 | NP_004334.1 calreticulin precursor | Complete | 8e | 9 |
| H3_71A8 | Tig_NM_182513_Contig_1 | NP_872319.1 spindle pole body component 24 homolog | False positive | - | - |
| H3_71D15 | Mex_NM_6276_Contig_2 | NP_001026854.1 splicing factor, arginine/serine-rich 7, 35 kDa | Completea | - | 1 |
a – start codon was not identified, but it is likely present in assembled sequence. b – this BAC contains a presumptive processed pseudogene. The aligning BAC and cDNA sequence are 91% identical and the BAC sequence contains no introns. c – not used in multispecies alignments due to lack of obvious vertebrate orthologies. d – exons were identified on two different contigs. e – not considered in multispecies alignments due to redundancy with H3_1D2. f – contig was originally identified as cytochrome c.