. 2009 Feb 5;4(2):e4347. doi: 10.1371/journal.pone.0004347

Table 5. Simplified indicators applied to congenital and to moderate pure motor DMD in series 2.

	Sensitivity	Specificity	Accuracy	Kappa	PPV^**	NPV^**
Age initial symptom <2 yrs+cognitive status I, II^**→psychomotor delay as 1^st symptom^	0.86	0.96	0.94	0.86	0.86	0.96
	0.47–0.97	0.80–0.99	0.77–0.99	0.47–1.00	0.47–0.97	0.80–0.99
MMT>6 at 8 yrs plus+cognitive status III, IV^**→ambulation loss >11 yrs^	1.00	0.92	0.94	0.86	0.82	0.94
	0.63–0.99	0.73–0.99	0.79–0.99	0.53–1.00	0.52–0.95	0.86–1.00

Yate's Chi square: all p = 0.00001, exact 95% confidence limits.

^**

PPV and NPV, positive or negative predictive value.

^***

I severe mental retardation, II mild mental retardation, III borderline normal, IV normal (see methods).