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. Author manuscript; available in PMC: 2009 Sep 26.
Published in final edited form as: Circ Res. 2008 Aug 21;103(7):702–709. doi: 10.1161/CIRCRESAHA.108.175489

Figure 3.

Figure 3

Pbx2 makes subsidiary contributions to the alignment of cardiac OFTs. A, Right ventricular angiography of a newborn Pbx1+/−2−/− mouse. Asterisk indicates a direct connection between the right ventricle (RV) and the ascending aorta (Asc. Ao). B, Exposure of the right ventricular cavity in A reveals a high ventricular septal defect (VSD) and an overriding aorta (OA). C and D, Serial sections through the subaortic region in newborn Pbx1+/−2−/− mice demonstrate an aorta that overrides both ventricles. Section plane in C is caudal to the plane in D. LVOT indicates left ventricular OFT.