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. 2008 Nov 14;179(3):212–219. doi: 10.1164/rccm.200802-228OC

Figure 5.

Figure 5.

Top: Hydroxyproline content (left) and fibrosis scores (right) from A12-treated mice and control mice after bleomycin instillation. Data were analyzed by two-way analysis of variance (ANOVA) with Tukey's honestly significant difference (HSD) post-hoc test, and statistical significance was set at *P < 0.05. Bottom: Histology of A12-treated mice and control mice at 14 days (A–H) and 28 days (I–P) after bleomycin instillation. Lung sections from A12-treated mice show relatively normal interstitium and less fibrosis (*) compared with control mice. Right middle lobe samples from two mice per group are shown. Original magnification: (A, C, E, G, I, K, M, and O) ×4; (B, D, F, H, J, L, N, and P) ×40. Scale bars: (A, C, E, G, I, K, M, and O) 200 μm; (B, D, F, H, J, L, N, and P) 25 μm. Stained with hematoxylin and eosin.