TABLE 2.
NASAL LAVAGE ANALYSIS OF TOTAL PROTEIN EDEMA AND CELLULAR INJURY IN NASAL AIRWAYS CAUSED BY VEHICLE AND RESPIRATORY SYNCYTIAL VIRUS (1 D AFTER INSTILLATION).*
Nasal Airway Phenotypes | Exposure | Nrf2+/+ | Nrf2−/− |
---|---|---|---|
Total proteins, μg/ml | Vehicle | 116 ± 44 | 157 ± 13 |
RSV | 347 ± 33† | 652 ± 209† | |
Total cells, ×103/ml | Vehicle | 4 ± 1 | 7 ± 4 |
RSV | 23 ± 3† | 62 ± 29† |
Definition of abbreviation: RSV = respiratory syncytial virus.
Data are presented as group means ± SEM (n = 5 mice/group).
Significantly different from genotype-matched vehicle control mice (P < 0.05).