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Trials of cytotoxic chemotherapy in metastatic carcinoid tumors.
| Regimen | Year | Response rate |
|---|---|---|
| Streptozocin + 5-FU vs. streptozocin + cyclophosphamide184 | 1979 | 33% vs. 26% |
| Streptozocin + 5-FU vs. doxorubicin 188 | 1984 | 22% vs. 21% |
| 5-FU + doxorubicin +cyclophosphamide + streptozocin189 | 1987 | 30% |
| Dacarbazine190 | 1994 | 16% |
| Doxorubicin + 5-FU vs. streptozocin + 5-FU186 | 2005 | 15% |
| Temozolomide + thalidomide191 | 2006 | 7% |
Abbreviations: 5-FU = 5-fluorouracil
