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Trials of cytotoxic chemotherapy in metastatic pancreatic endocrine tumors.
| Regimen | Year | Response rate |
|---|---|---|
| Streptozocin + 5-FU vs. streptozocin192 | 1980 | 63% vs. 36% |
| Streptozocin + doxorubicin vs. streptozocin + 5-FU193 | 1992 | 69% vs. 45% |
| Dacarbazine195 | 2001 | 31% |
| Streptozocin + doxorubicin + 5-FU194 | 2006 | 39% |
| Temozolomide + thalidomide191 | 2006 | 7% |
Abbreviations: 5-FU = 5-fluorouracil
