FIGURE 4.

Analysis of optimal values of tether rate curves. (a) Peak locations of the p_ad/(m_rm_lr) vs. $r\stackrel{.}{\gamma }$ curves (optimal $r\stackrel{.}{\gamma }$) were plotted against the sphere diffusivity D_s. (b) Peak locations of the p_ad/(m_rm_lr) vs. $D_{\mathrm{s}}∕r\stackrel{.}{\gamma }$ curves (optimal $D_{\mathrm{s}}∕r\stackrel{.}{\gamma }$) where plotted against the sphere diffusivity D_s. (c) Maximum p_ad/(m_rm_lr) values were plotted against the molecular diffusivity D_m. (d) Reciprocal of maximum p_ad/(m_rm_lr) values were plotted against reciprocal of the molecular diffusivity. Positive correlations were evident in all plots for both microspheres (open symbols) and neutrophils (solid circles). A straight line was fit to each set of the data for microspheres or neutrophils in (b) and (d). The best-fit equations are indicated along with the R² values. Reproduced from Yago et al.²¹