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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2008 Sep 18;45(11):1573–1580. doi: 10.1016/j.freeradbiomed.2008.09.005

Fig. 4.

Fig. 4

The SOD2 promoter of breast cancer cells is associated with hypoacetylated histones. The association of acetylated H3K9 with SOD2 and GAPDH in breast cell lines was determined using chromatin immunoprecipitation (ChIP). The level of acetylated H3K9 at seven regions (A1-A7) of the SOD2 and GAPDH promoters in breast cell lines were calculated as described in methods and materials. Values given are the averages of three independent experiments ± the standard error. (* p < 0.05 between MCF-10A and breast cancer cell lines at respective amplicons. For individual statistical analysis between MCF-10A and breast cancer cell lines see Supplemental Table S2).