Skip to main content
. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2008 Sep 18;45(11):1573–1580. doi: 10.1016/j.freeradbiomed.2008.09.005

Fig. 5.

Fig. 5

The SOD2 gene of breast cancer cell lines is less accessible than immortalized breast epithelial cells. Chromatin accessibility of the seven regions (A1-A7) of the SOD2 promoter and GAPDH was determined by DNAse I hypersensitivity. Accessibility index of each region was determined using SYBR green real-time PCR. Accessibility index for each amplicon was then as described in methods and materials. Values given are the averages of three independent experiments ± the standard error. (* p < 0.05 between MCF-10A and breast cancer cell lines at respective amplicons. For individual statistical analysis between MCF-10A and breast cancer cell lines see Supplemental Table S3).