Fig. 1.

(A) Consensus sequences for Eσ⁷⁰ recognition elements and RNAP regions that interact with these elements: UP Element with α subunit C-terminal domains (αCTDs, the α subunit DNA binding domains), −35 hexamer with σ⁷⁰ 4.2, extended −10 element with σ⁷⁰ 3.0, −10 hexamer with σ⁷⁰ 2.3–2.4, and discriminator region element withσ⁷⁰ 1.2. The transcription start site is indicated as (+1). The most common spacing between recognition elements, in bp, with (range) is indicated. For a recent review, see [5]. Both the spacing of the −35 element with respect to the extended −10 element (14bp), and with respect to the −10 element (17bp) are shown.