TABLE 4.
GENE SETS WITH SIGNIFICANT ENRICHMENT IN SURFACE EPITHELIUM SAMPLES
| Gene Set | N | Enrichment Score | Nominal P Value | FDR q- Value | FWER P Value |
|---|---|---|---|---|---|
| Urea cycle and metabolism of amino groups | 15 | 0.820 | 0.000 | 0.115 | 0.046 |
| Arginine and proline metabolism | 34 | 0.756 | 0.000 | 0.074 | 0.065 |
| Glutathione metabolism | 42 | 0.625 | 0.000 | 0.173 | 0.276 |
| Glycolysis and gluconeogenesis | 48 | 0.693 | 0.000 | 0.136 | 0.359 |
| Tryptophan metabolism | 39 | 0.613 | 0.002 | 0.123 | 0.37 |
| Mitochondria | 391 | 0.561 | 0.000 | 0.122 | 0.395 |
| Glycerolipid metabolism | 44 | 0.561 | 0.000 | 0.120 | 0.447 |
| Bile acid biosynthesis | 19 | 0.792 | 0.000 | 0.108 | 0.565 |
| Phenylalanine metabolism | 24 | 0.782 | 0.000 | 0.104 | 0.565 |
| Stilbene, coumarine, and lignin biosynthesis | 24 | 0.782 | 0.000 | 0.099 | 0.565 |
| Drug resistance and metabolism | 92 | 0.464 | 0.000 | 0.094 | 0.573 |
| Down-regulated by glutamine | 262 | 0.540 | 0.000 | 0.087 | 0.578 |
| Fatty acid metabolism | 40 | 0.641 | 0.004 | 0.086 | 0.584 |
Definition of abbreviations: FDR, false discovery rate; FWER, familywise error rate.