Table 1.
Presentation characteristics of four human immunodeficiency virus (HIV) seropositive patients with haemophagocytic syndrome in association with multi-centric Castleman's disease.
Case No | Sex | Ethnicity | Age | Duration HIV+ (years) | CD4 cell count (/mm3) | Plasma HIV viral load (copies/mm3) | Established on HAART | Duration of symptoms (months) | ECOG PS | KS | Plasma HHV-8 VL (copies/ml) |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | M | Black African | 37 | 0·8 | 492 | < 50 | Yes | 3 | 2 | No | 380 000 |
2 | M | Caucasian | 24 | 0·2 | 193 | 41 860 | No | 2 | 2 | No | 90 000 000 |
3 | M | Caucasian | 51 | 1·1 | 71 | < 500 000 | No | 1 | 3 | Yes | 7 300 000 |
4 | M | Black African | 46 | 8·1 | 233 | < 50 | Yes | 4 | 3 | No | 30 000 |
HAART, highly active retroviral therapy; HHV-8, human herpesvirus-8; KS, Kaposi's sarcoma; ECOG, Eastern Cooperative Oncology Group; VL, viral load.