Table 3.
Effects of Bifidobacterium animalis on clinical parameters of experimental autoimmune encephalomyelitis (EAE).
| Group | n | Disease onseta (days) | Duration of symptomsb (days) | CDIc | ||
|---|---|---|---|---|---|---|
| Mean | s.e. | Mean | s.e. | |||
| Females | ||||||
| EAE + saline | 4 | 14·4 | 0·6 | 6·8 | 1·1 | 4·5 |
| EAE + B. animalis | 4 | 13·6 | 0·3 | 6·0 | 0·7 | 4·9 |
| Males | ||||||
| EAE + saline | 4 | 13·4 | 0·4 | 7·4 | 0·6 | 6·1 |
| EAE + B. animalis | 4 | 13·9 | 0·6 | 5·5** | 0·3 | 5·9 |
a
Disease onset is the first day that clinical signs were observed in a treatment group;
b
the duration of symptoms is the mean of the total number of days clinical symptoms were a treatment group;
c
CDI (cumulative disease index) is the sum of the cumulative daily scores per group divided by the number of days that the clinical symptoms were observed in this group. All data are expressed as mean ± standard error (s.e.), except for the CDI. Significantly different from the EAE + saline group:
**
P < 0·01. n: number of rats per group.