Table 5.
Immunohistochemical expression of FANCC and PTCH1 with respect to their alterations
| FANCC alteration | PTCH1 alteration | |||
| Sample No. | Deletion/Methylation | FANCC protein expression | Deletion/Methylation | PTCH1 protein expression |
| 1186 | +/- | - | -/- | +++ |
| 374 | -/+ | - | -/+ | - |
| 4187 | +/- | + | -/+ | - |
| 3266 | +/+ | - | -/- | +++ |
| 5451 | -/- | +++ | -/- | +++ |
| 5596 | -/- | +++ | -/+ | - |
| 3156 | +/+ | - | -/- | +++ |
| 4604 | +/+ | - | +/+ | - |
| 4131 | -/+ | ++ | +/- | - |
| 2490 | +/- | - | -/+ | - |
| 2400 | +/+ | - | -/+ | ++ |
| 796 | +/- | ++ | -/+ | - |
| 880 | -/- | +++ | +/+ | - |
| 314 | +/- | ++ | +/- | ++ |
| 5337 | +/- | - | -/- | +++ |
| 1865 | +/+ | - | -/+ | - |
| 4671 | -/- | +++ | +/- | + |
| 3025 | +/+ | - | -/+ | - |
| 6155 | -/+ | - | -/- | +++ |
| 1144 | -/- | +++ | -/+ | - |
| P value | P = 0.004 * | P = 0.001 * | ||
Abbreviations used are: Sample no is patient's registration number