Table 3.
Structural Differences between Apo and Ca2+-S100A4 and Other S100 Proteins
| rms deviation between Cα atoms (Å)/Z scorea |
|||
|---|---|---|---|
| apob | Ca2+-boundc | sequence identity (%) |
|
| S100A1 | 3.2/7.3d (86) | 2.6/10.3e (92) | 49 |
| S100A6 | 2.1/9.6f (84) | 1.5/15.1g (89) | 50 |
| S100A7 | n/a | 2.3/11.3h (87) | 27 |
| S100A8 | n/a | 2.2/13.3i (88) | 34 |
| S100A9 | n/a | 1.3/13.0j (81) | 32 |
| S100A11 | 3.2/7.0k (87) | 2.0/14.5l (95) | 27 |
| S100A12 | n/a | 1.5/14.3m (87) | 40 |
| S100A13 | 3.7/7.0n (83) | 1.5/14.5o (86) | 34 |
| S100B | 3.5/8.4p (88) | 2.4/11.7q (92) | 48 |
| calbindin D9K |
3.1/4.6r (67) | 1.9/11.7s (73) | 38 |
| calcyclin | 2.9/9.1t (87) | 2.8/10.5u (88) | 51 |
a
Calculated using DaliLite (47); values in parentheses indicate the number of superimposed atoms.
b
PDB entry 1M31 (23).
c
PDB entry 2Q91 (this work).
d
PDB entry 1K2H (77).
e
PDB entry 1ZFS (35).
f
PDB entry 1K9P (76).
g
PDB entry 1K96 (76).
h
PDB entry 1PSR (100).
i
PDB entry 1MR8 (105).
j
PDB entry 1IRJ (106).
k
PDB entry 1NSH (95).
l
PDB entry 1QLS (96).
m
PDB entry 1E8A (107).
n
PDB entry 1YUR (97).
o
PDB entry 2H2K (98).
p
PDB entry 1SYM (78).
q
PDB entry 1QLK (34).
r
PDB entry 1KCY (108).
s
PDB entry 4ICB (108).
t
PDB entry 2CNP (75).
u
PDB entry 1JWD (99).