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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Cancer Res. 2009 Jan 13;69(3):1182–1189. doi: 10.1158/0008-5472.CAN-08-2001

FIGURE 4. Effects of doxorubicin on uMUC-1 availability in BT-20 cells - in vitro tests.

FIGURE 4

A, qRT-PCR demonstrates a significant downregulation of uMUC-1 induced by doxorubicin (p = 0.028). This effect is MUC-1 specific because 18s RNA is not downregulated (inset). B, Western blot demonstrates a noticeable downregulation of uMUC-1 but not of tubulin. Arrow points to the MUC-1 band. C, TUNEL assay indicates that doxorubicin treatment of BT-20 cells induced apoptosis efficiently.