Table 2.
Extinction Responding in Group-Housed and Socially Isolated Long- Evans Ratsa
Group Housedb | Socially Isolated | Statisticsc | |
---|---|---|---|
Ethanol Self-Administration | |||
Total Lever Responses | 123.3 ± 9.1 | 127.8 ± 12.5 | n.s. |
Response Bouts | 9.2 ± 0.9 | 9.1 ± 0.6 | n.s. |
1st Bout Responses | 15.7 ± 4.6 | 33.4 ± 8.9 | n.s. (P<0.1) |
1st Bout Response Rate (press/min) | 28.5 ±4.4 | 54.7 ± 11.4 | t=2.13, P<0.05 |
Response Latency (sec) |
26.4 ± 6.1 |
45.2 ± 6.2 |
t=2.09, P<0.05 |
Sucrose Self-Administration | |||
Total Lever Responses | 141.8 ± 9.6 | 141.0 ± 20.0 | n.s. |
Response Bouts | 4.2 ± 0.8 | 4.8 ± 0.9 | n.s. |
1st Bout Responses | 30.3 ± 11.9 | 24.7 ± 8.3 | n.s. |
1st Bout Response Rate (press/min) | 5.6 ± 0.3 | 6.1 ± 0.3 | n.s. |
Response Latency (sec) | 40.5 ± 9.6 | 36.4 ± 9.2 | n.s. |
Extinction responding was measured with two separate individual trials separated by a week of standard self administration. Averages for individual animals were used for the group comparisons.
For the ethanol self-administration study, n=11 for the group housed animals and n=16 for the socially isolated animals (see text). For the sucrose self-administration study, n= 11 for both the group housed and socially isolated animals.
Statistical comparisons were made using Student's t-test. P<0.05 was considered significant. “n.s.” = not significant