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Hetero-oilgomerization of βB1 with βA3 as a function of time. βB1 was mixed with either βA3 WT (open circles) or βA3 DM (closed circles) and incubated at 37 °C from 0-300 min and then subjected to SEC-MALS. The relative amount of complex was determined from the peak area. Formation of the βB1:βA3 DM complex was slower than formation of the βB1:βA3 WT complex. Arrow indicates 90 min time point showing 40 % difference between WT and DM.
