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Asf1 and CAF-1 do not affect recovery when DSB repair occurs without strongly activating the DNA damage checkpoint. Percentage viabilities of YJK139 wild type and its derivatives lacking both Asf1 and Cac1 were measured as described in Fig. 1A. The diagram shows the HO-induced DSB at the MAT locus on ChIII and the consequence of the DSB repair by intrachromosomal HR by using the HMLα-inc donor located at the left arm of chromosome III. The CEN3 locus is marked as a black dot.
