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Modulation of expression of iNOS and inflammatory cytokines in colon tissue. (A) Expressions of proinflammatory cytokines and iNOS were significantly increased after infection with H. hepaticus (Hh). Depletion of Gr-1+ cells (B) and TNF-α (C) decreased iNOS expression. (D) Infected double-knockout mice showed significant increases in iNOS and IFN-γ gene expression. (E) TEFF cells increased levels of IFN (IFN-γ) and iNOS expression.
