Fig. 3.

Graphical illustrations of DNA-lipid conjugates in the 5′ /5′ orientation used to tether vesicles to supported bilayers and allow vesicle docking. (A) Vesicles presenting sequence β are tethered to a supported lipid membrane presenting the complementary sequence β′. These tethered vesicles are observed to diffuse in the plane parallel to the supported membrane. Although they collide, they do not exchange lipids or lose contents (20). (B) When a complementary pair, α and α′, of DNA-lipid conjugates are displayed on separate vesicles, docking is observed upon collisions depending on the number density, sequence and length of the DNA that is displayed (22).