Table 3. Univariate analysis predicting all cause and cardiovascular disease mortality.
Patients | n | Person time intervals | All cause mortality | CVD mortality | |||
Univariate, OR (95% CI) | Adjusted age and gender, OR (95% CI) | Univariate, OR (95% CI) | Adjusted age and gender, OR (95% CI) | ||||
Baseline NSAID use | All | 923 | 5634 | 0.73 (0.55 to 0.99) | 0.81 (0.60 to 1.03) | 0.67 (0.43 to 1.04) | 0.73 (0.48 to 1.15) |
Females | 599 | 3742 | 0.86 (0.56 to 1.32) | 0.86 (0.55 to 1.32) | 0.55 (0.30 to 1.02) | 0.54 (0.29 to 1.02) | |
Males | 324 | 1892 | 0.61 (0.41 to 0.92) | 0.74 (0.50 to 1.12) | 0.79 (0.42 to 1.47) | 0.94 (0.50 to 1.78) | |
Ever NSAID use | All | 923 | 5634 | 0.62 (0.44 to 0.86) | 0.70 (0.50 to 1.00) | 0.48 (0.29 to 0.77) | 0.54 (0.33 to 0.88) |
Females | 599 | 3742 | 0.74 (0.44 to 1.22) | 0.81 (0.48 to 1.36) | 0.42 (0.22 to 0.82) | 0.46 (0.23 to 0.90) | |
Males | 324 | 1892 | 0.49 (0.31 to 0.77) | 0.61 (0.39 to 0.98) | 0.50 (0.25 to 1.01) | 0.62 (0.31 to 1.27) | |
Time-varying NSAID use | All | 923 | 5634 | 0.58 (0.43 to 0.78) | 0.66 (0.49 to 0.90) | 0.51 (0.32 to 0.81) | 0.58 (0.37 to 0.93) |
Females | 599 | 3742 | 0.60 (0.39 to 0.91) | 0.68 (0.44 to 1.05) | 0.50 (0.26 to 0.97) | 0.58 (0.30 to 1.12) | |
Males | 324 | 1892 | 0.54 (0.36 to 0.81) | 0.65 (0.43 to 0.98) | 0.51 (0.27 to 0.94) | 0.59 (0.31 to 1.12) |
CVD, cardiovascular disease; NSAID, non-steroidal anti-inflammatory drug; OR, odds ratio.