Table 4.
Differentially expressed genes known to be involved in the immune response in older (65, 65 and 69 years) compared to younger (19, 25 and 38 years) female parotid glands
| Gene Name | Accession No. | Gene ID | Ratio | Direction |
|---|---|---|---|---|
| Chemokine (C-X-C motif) ligand 10 | NM_001565 | CXCL10 | 8.37 | Down |
| Ubiquitin D | NM_006398 | UBD | 3.89 | Down |
| Major histocompatibility complex, class II, DQ alpha 1 | BG397856 | HLA-DQA1 | 3.5 | Down |
| Interferon, alpha-inducible protein 6 | NM_022873 | IFI6 | 3.49 | Down |
| Interferon-stimulated transcription factor 3, gamma 48kDa | NM_006084 | ISGF3G | 3.34 | Down |
| interferon-stimulated protein, 15 kDa | NM_005101 | ISG15 | 3.05 | Down |
| Histone deacetylase 9 | BM726008 | HDAC9 | 2.73 | Up |
| interferon regulatory factor 7 | NM_004030 | IRF-7 | 2.36 | Down |
| guanylate binding protein 1, interferon-inducible, 67kD | AW014593 | GBP1 | 2.15 | Down |
| Guanylate binding protein 1, interferon-inducible | BC002666 | GBP1 | 2.1 | Down |
| Interferon induced transmembrane protein 3 | BF338947 | IFITM3 | 2.1 | Down |
| Myxovirus (influenza virus) resistance 2 | NM_002463 | MX2 | 2.09 | Down |
| Interferon induced transmembrane protein 1 | AA749101 | IFITM1 | 2.08 | Down |
| Transporter 1, ATP-binding cassette, sub-family B | NM_000593 | TAP1 | 2.03 | Down |
| Major histocompatibility complex, class II, DQ beta 1 | AI583173 | HLA-DQB1 | 1.99 | Down |
| Myeloid leukemia factor 1 | NM_022443 | MLF1 | 1.97 | Up |
| Proteasome subunit, beta type, 9 | NM_002800 | PSMB9 | 1.97 | Down |
| NCK adaptor protein 1 | NM_006153 | NCK1 | 1.95 | Up |
| Suppressor of cytokine signaling 5 | AW664421 | SOCS5 | 1.95 | Up |
| Interferon regulatory factor 1 | NM_002198 | IRF-1 | 1.89 | Down |
| Secreted and transmembrane 1 | BF939675 | SECTM1 | 1.82 | Down |
| Leptin | NM_000230 | LEP | 1.74 | Up |
| Clusterin | M25915 | CLU | 1.67 | Up |
| CD74 molecule | K01144 | CD74 | 1.63 | Down |
| Mucosa associated lymphoid tissue lymphoma translocation ge | NM_006785 | MALT1 | 1.63 | Up |
| Proteasome subunit, beta type, 9 | AI375915 | PSMB9 | 1.62 | Down |
| Proteasome subunit, beta type, 8 | U17496 | PSMB8 | 1.61 | Down |
| Tumor necrosis factor (ligand) superfamily, member 13b | AF134715 | TNFSF13B | 1.58 | Down |
| Interferon induced transmembrane protein 2 | NM_006435 | IFITM2 | 1.55 | Down |
| Chemokine (C-C motif) receptor 2 | NM_000647 | CCR2 | 1.5 | Up |