Table 7.

Gene expression in male and female human parotid glands and their ontological categorization

Ontology	Diff	M	F	Total	M	F
	exp genes^a	up^b	up^c	on Array^d	z-score^e	z-score^f
Biological Processes
Physiological process	387	176	211	9550	1.54	2.21
Metabolism	275	122	153	6530	0.99	2.25
Regulation of biological process	139	51	88	3375	−1.34	2.53
Protein metabolism	122	64	58	2623	3.01	0.51
Transcription	76	23	53	1977	−2.24	2.04
Cell organization and biogenesis	66	38	28	1405	2.86	−0.26
Protein transport	33	16	17	534	2.22	1.82
Protein biosynthesis	28	17	11	525	2.63	0.01
Vesicle-mediated transport	25	15	10	352	3.62	1.01
Protein kinase cascade	19	10	9	278	2.35	1.36
Response to wounding	19	5	14	363	−0.57	2.4
Macromolecule catabolism	18	11	7	332	2.18	0.03
Secretion	16	12	4	250	3.69	−0.54
Endocytosis	12	6	6	130	2.48	2.03
Cellular Components
Intracellular	329	139	190	7016	1.78	4.34
Organelle	259	108	151	5757	0.55	2.8
Membrane-bound organelle	231	97	134	5065	0.77	2.62
Cytoplasm	161	82	79	3131	4.01	1.25
Nucleus	155	56	99	3468	−1.04	2.93
Integral to membrane	117	54	63	3457	−1.32	−2.02
Protein complex	78	41	37	1569	2.58	0.33
Mitochondrion	34	21	13	618	3.05	−0.24
Endoplasmic reticulum	31	19	12	579	2.73	−0.29
Organelle membrane	30	15	15	474	2.26	1.38
Extracellular region	28	15	13	998	−0.76	−2.11
Ribonucleoprotein complex	23	18	5	330	5.04	−0.91
Envelope	19	10	9	252	2.6	1.44
Molecular Processes
Protein binding	204	97	107	4621	2.51	0.77
Ion binding	120	41	79	3370	−2.64	0.74
Nucleotide binding	99	39	60	1790	1.61	3.65
Transferase activity	70	22	48	1665	−1.35	2.1
ATP coupled activity and binding	60	22	38	1196	0.33	2.47
Kinase activity	37	11	26	733	−0.47	2.6
Pyrophosphatase activity	33	19	14	502	3.63	0.95
GTP binding	23	14	9	290	4.12	1.08
Transcription factor activity	23	6	17	791	−2.15	−0.07
Structural constituent of ribosome	12	9	3	150	4.06	−0.16
Calmodulin binding	11	3	8	120	0.66	3.37
Hydrogen ion transporter activity	10	4	6	96	1.85	2.74

Diff exp genes indicate the total number of genes differentially expressed on the array in that category.

up regulated genes in male parotid glands, as compared to those of female (M-up).

Up regulated genes in female parotid glands, as compared to those of male (F-up).

'Total on array indicates the total number of genes on the array in that Ontological category.

z-score-M and z-score-F indicate the z-score for the male and female respectively.

The z-scores with value >2.0 or <-2.0 are reported for ontologies with more than 10 differentially expressed genes.