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Streptomyces AcH 505 expresses a combination of mechanisms. The metabolite WS 5995 B acts as a selector, since only WS-5995 B sensitive fungi are inhibited by AcH 505. The second dominant metabolite of AcH 505, auxofuran, stimulates mycelial growth of fungi. The presence of AcH 505 promotes colonization of the root by the fungus. This presumably occurs by suppression of the host defence response by AcH 505, reflected by suppressed defence gene activities.
