Skip to main content
. 2005 Apr-Jun;2(2):33–35. doi: 10.4161/org.2.2.2167

Figure 2.

Figure 2

Abnormalities in differentiation and CE formation in Grhl3-null epidermis. Skin from wild type (+/+) and mutant (-/-) embryos taken at E15.5 and E18.5 as indicated. Epithelial ridges (arrows) in wild type skin at E15.5 (top left panel) are absent in the E15.5 mutant skin (top right panel). Basal disorganisation and suprabasal hyperproliferation and a compacted SC are evident in the E18.5 mutant skin (bottom right) compared to the wild type (bottom left). d, dermis; sb, stratum basale; ss, stratum spinosum; sg, stratum granulosum; sc, stratum corneum. Previously published in Science 2005; 308:411–3.