. Author manuscript; available in PMC: 2009 Sep 1.

Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Jul 31;872(1-2):141–147. doi: 10.1016/j.jchromb.2008.07.032

Table 2.

Assay performance data for the quantitation of LLQ, QCL, QCM and QCH ABT-888 and M8 concentrations in human plasma.

Concentration (ng/mL)		Accuracy (%)	Intra-assay precision (%)	Inter-assay precision (%)

ABT-888	10 (LLQ)	98.2	4.7	4.9
	20 (QCL)	98.4	3.6	0.1
	200 (QCM)	98.5	3.2	2.3
	800 (QCH)	95.5	3.1	4.0

M8	10 (LLQ)	100.9	7.3	13.7
	20 (QCL)	96.9	6.6	6.5
	200 (QCM)	96.9	4.3	4.4
	800 (QCH)	91.4	5.6	-^*

N=24; 8-fold results, each in 3 separate runs, for each concentration.

The mean square of the within runs was greater than the mean square of the between runs, indicating that there was no significant additional variation due to the performance of the assay in different runs [9].