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Recoveries of ABT-888 and M8 from human plasma and their respective ion suppressions in human plasma extract, with coefficients of variation (CV).
| Concentration (ng/mL) | Recovery (%) | CV (%) | Ion suppression (%) | CV (%) | |
|---|---|---|---|---|---|
| ABT-888 | 20 (QCL) | 71.4 | 15.1 | 23.1 | 14.1 |
| 200 (QCM) | 76.0 | 7.3 | 2.9 | 6.1 | |
| 800 (QCH) | 79.0 | 21.1 | 11.5 | 9.7 | |
| M8 | 20 (QCL) | 67.3 | 12.3 | 26.4 | 8.8 |
| 200 (QCM) | 62.2 | 6.7 | 12.3 | 7.8 | |
| 800 (QCH) | 63.4 | 22.6 | 21.0 | 8.6 | |
N=3, for each concentration.
