Figure 2.

Probability of CWD as predicted by the number of polymorphic alleles. Total polymorphisms, silent polymorphisms, coding polymorphisms and total polymorphisms omitting locus 153 were used as independent variables in separate logistic regression models with CWD as the outcome variable. Odds ratios were estimated using the number of heterozygous and homozygous SNP summed across all loci. Coding for locus 153 was reversed because wild-type alleles conferred susceptibility (2 = homozygous for the consensus genotype, 1 = heterozygous, 0 = homozygous for the polymorphism), which resulted in a higher predicted probability of CWD than in a model omitting locus 153.