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Polyphenols rich of gallate moieties can interact with the cell surface (A). Then gallates may initiate the phospholipid rigidifying process (physically modified lipids are emphasized by shape and color) (B) and lead to aggregation of some proteins and lipids in clusters (D). Polyphenol molecules could serve as bridges between surfaces of two neighbor cells and initiate cells binding and formation of similar clusters in the membrane of the opposite cell.
