Table 1.
| Treatments | Infection i.p. 6PB1 104.5 Ld50 | Non-Infected | |||||
| Number of Animals | Duration of Symptoms: Mean ± SD (days) | Survival Time: Individual Range (dpi) | Survival Time: Mean ± SD (dpi) | Neuronal Death* | Neuronal Death** | ||
| Artificial CSF | 5 | 6 ± 4 | 143–148 | 145 ± 2 | 0/2 | 0/1 | |
| IgG 4H11 | 8 | 29 ± 16 | 133–159 | 140 ± 8 | 0/4 | 1/4 | |
| IgG control | 7 | 25 ± 16 | 129–159 | 143 ± 10 | 0/2 | 0/2 | |
| F(ab′)2 4H11 | 7 | 50 ± 9 | 127–167 | 143 ± 14 | 2/3 | 2/4 | |
| F(ab′)2 control | 9 | 26 ± 17 | 136–166 | 144 ± 11 | 0/3 | 0/1 | |
| Fab 4H11 | Not Tested | Not Tested | Not Tested | Not Tested | Not Tested | 2/2 | |
*
Expressed as a ratio of the number of animals tested by histology.
**
All animals have been tested by histology.