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. Author manuscript; available in PMC: 2009 Feb 2.
Published in final edited form as: Subst Use Misuse. 2004 Jan;39(1):25–59. doi: 10.1081/JA-120027765

Table 5.

Estimated cocaine-associated deficit in stable aptitude for language development under multiple covariate models for total language standard scores in children at 3, 5, and 7 years of age.

Est. difference (D) 95% C.I. p value
Initial model: includes severity of cocaine exposure, fetal growth, gestational age, IQ, child’s age and gender, and self-reported levels of prenatal alcohol, tobacco, and marijuana exposure −0.071 −0.133, −0.009 0.026
Additional covariates:
 Birth covariates:
  Maternal age −0.073 −0.136, −0.009 0.025
  Maternal education level −0.064 −0.125, −0.004 0.037
  Primigravida (yes/no) −0.073 −0.136, −0.009 0.025
  Marital status (never/ever) −0.069 −0.132, −0.007 0.028
  Maternal employment (never/ever) −0.068 −0.130, −0.006 0.031
  Prenatal care visits (0–3 vs. 4+) −0.073 −0.140, −0.005 0.034
  Apgar score at 5 minutes −0.067 −0.129, −0.004 0.036
Postnatal covariates: (measured at 3-year visit unless otherwise noted):
 Child resides with biological mother (yes/no) −0.088 −0.167, −0.010 0.027
 Caregiver education level (years) −0.072 −0.132, −0.012 0.019
 Caregiver employment (yes/no) −0.072 −0.133, −0.012 0.020
 Number of caregiver changes (0–36 mos.) −0.068 −0.132, −0.003 0.041
 Past-year reported cocaine use −0.074 −0.140, −0.007 0.030
 Past-year reported marijuana use −0.078 −0.143, −0.013 0.018
 Past-year reported alcohol use −0.078 −0.142, −0.013 0.019
 Past-year reported cigarette use −0.069 −0.133, −0.006 0.032
 Day care placement (yes/no) −0.075 −0.138, −0.012 0.020
 IQ score −0.041 −0.079, −0.004 0.032
 Hearing −0.070 −0.131, −0.008 0.026
 Lead exposure level (ng/dL) −0.074 −0.139, −0.009 0.025
 HOME language stimulation score (4½ years) −0.060 −0.120, −0.001 0.047
 Head Start/Pre-kindergarten placement (5 years) −0.068 −0.128, −0.008 0.027