Table 5.
Estimated cocaine-associated deficit in stable aptitude for language development under multiple covariate models for total language standard scores in children at 3, 5, and 7 years of age.
| Est. difference (D) | 95% C.I. | p value | |
|---|---|---|---|
| Initial model: includes severity of cocaine exposure, fetal growth, gestational age, IQ, child’s age and gender, and self-reported levels of prenatal alcohol, tobacco, and marijuana exposure | −0.071 | −0.133, −0.009 | 0.026 |
| Additional covariates: | |||
| Birth covariates: | |||
| Maternal age | −0.073 | −0.136, −0.009 | 0.025 |
| Maternal education level | −0.064 | −0.125, −0.004 | 0.037 |
| Primigravida (yes/no) | −0.073 | −0.136, −0.009 | 0.025 |
| Marital status (never/ever) | −0.069 | −0.132, −0.007 | 0.028 |
| Maternal employment (never/ever) | −0.068 | −0.130, −0.006 | 0.031 |
| Prenatal care visits (0–3 vs. 4+) | −0.073 | −0.140, −0.005 | 0.034 |
| Apgar score at 5 minutes | −0.067 | −0.129, −0.004 | 0.036 |
| Postnatal covariates: (measured at 3-year visit unless otherwise noted): | |||
| Child resides with biological mother (yes/no) | −0.088 | −0.167, −0.010 | 0.027 |
| Caregiver education level (years) | −0.072 | −0.132, −0.012 | 0.019 |
| Caregiver employment (yes/no) | −0.072 | −0.133, −0.012 | 0.020 |
| Number of caregiver changes (0–36 mos.) | −0.068 | −0.132, −0.003 | 0.041 |
| Past-year reported cocaine use | −0.074 | −0.140, −0.007 | 0.030 |
| Past-year reported marijuana use | −0.078 | −0.143, −0.013 | 0.018 |
| Past-year reported alcohol use | −0.078 | −0.142, −0.013 | 0.019 |
| Past-year reported cigarette use | −0.069 | −0.133, −0.006 | 0.032 |
| Day care placement (yes/no) | −0.075 | −0.138, −0.012 | 0.020 |
| IQ score | −0.041 | −0.079, −0.004 | 0.032 |
| Hearing | −0.070 | −0.131, −0.008 | 0.026 |
| Lead exposure level (ng/dL) | −0.074 | −0.139, −0.009 | 0.025 |
| HOME language stimulation score (4½ years) | −0.060 | −0.120, −0.001 | 0.047 |
| Head Start/Pre-kindergarten placement (5 years) | −0.068 | −0.128, −0.008 | 0.027 |