Table 3. Antibody production in raccoons experimentally infected with avian influenza virus (H4N8)*.
| Raccoon ID | Day postinoculation |
Final subtype† | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | ||
| 264 | N | N | N | N | N | N | N | N | ||||||||
| 275 | N | N | N | N | N | N | N | N | ||||||||
| 256 | N | N | N | N | N | WP | SP | SP | H4N8 | |||||||
| 253 | N | N | N | N | N | N | N | N | ||||||||
| 260‡ | N | NS | N | N | N | N | N | N | ||||||||
| 262‡ | P | P | P | P | P | P | WP | WP | H4N8§ | |||||||
| 258 | N | N | N | N | N | N | N | N | ||||||||
| 257 | N | N | N | N | N | N | N | N | ||||||||
| 259 | N | N | N | N | N | ¶ | – | |||||||||
| 263 | SP | SP | SP | SP | SP | SP | SP | SP | H4N8§ | |||||||
*Antibodies were detected by agar gel immunodiffusion, and final subtyping was determined at the National Veterinary Services Laboratories (Ames, IA, USA). N, negative; WP, weakly positive; SP, strongly positive; NS, not sampled; P, positive. †H, hemagglutinin; N, neuraminidase. ‡Uninoculated raccoons housed in adjacent cages to infected raccoons. §These raccoons had preexisting antibodies (262:H10N7, 1:10; 263:H4N6 1:40). ¶Raccoon humanely killed 8 days postinoculation.