Table 2. Univariate and multivariate analysis for distant metastasis (logistic regression model).

	Univariate analysis			Multivariate analysis
	RR	95% CI	P-value	RR	96% CI	P-value
Histological grade (Differentiated/undifferentiated)	2.35	1.31–2.35	<0.0001	0.58	0.24–1.45	0.239
pT (Depth of tumour invasion)	49.91	27.36–99.07	<0.0001	28.17	14.30–60.95	<0.0001
pN (Lymph node metastasis)	22.78	11.56–51.49	<0.0001	6.5	2.99–15.77	<0.0001
Lymphatic invasion	12.12	6.89–23.12	<0.0001	—	—	—
Venous invasion	4.55	2.91–7.10	<0.0001	1.61	0.90–2.88	0.106
uPAR mRNA expression in bone marrow	1.53	1.01–2.35	0.046	—	—	—
uPAR mRNA expression in peripheral blood	1.95	1.28–2.99	0.002	1.85	1.08–3.23	0.0207