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. 2008 Dec 2;100(1):153–159. doi: 10.1038/sj.bjc.6604806

Table 4. Relationship between epithelial marker and uPAR expression in bone marrow and peripheral blood and clinicopathologic findings.

    Epithelial marker and uPAR expression in BM
Epithelial marker and uPAR expression in PB
    Both positive Others   Both positive Others  
  Total (n=846) n=126 n=720 P-value n=200 n=646 P-value
Age (mean±s.d.*)   60.9±0.97 61.6±0.43 NS 60.8±0.81 61.7±0.45 NS
Gender       0.403      
 Male 567 88 (69.8) 479 (66.5)   130 (65.0) 437 (67.6) 0.526
 Female 279 38 (30.2) 241 (33.5)   70 (35.0) 209 (32.4)  
               
Histology       0.645      
 Differentiated 188 30 (23.8) 158 (21.9)   45 (22.5) 143 (22.1) 0.914
 Undifferentiated 658 96 (76.2) 562 (78.1)   155 (77.5) 503 (77.9)  
               
pT       0.183      
 pT1/T2 657 92 (73.0) 565 (78.5)   147 (73.5) 510 (79.0) 0.11
 pT3/T4 189 34 (27.0) 155 (21.5)   53 (26.5) 136 (21.0)  
               
pN         0.012    
 pN0 496 61 (48.4) 435 (60.4)   112 (56.0) 384 (59.4) 0.389
 pN1 350 65 (51.6) 285 (39.6)   88 (44.0) 262 (40.6)  
               
pM (Distant metastasis)       0.108      
 pM0 743 105 (83.3) 638 (88.6)   170 (85.0) 573 (88.7) 0.171
 pM1 103 21 (16.7) 82 (11.4)   30 (15.0) 73 (11.3)  
               
Postoperative recurrence       0.145      
 Non recurrence 833 122 (96.8) 711 (98.8)   197 (98.5) 636 (98.5) 0.961
 Recurrence 13 4 (3.2) 9 (1.2)   3 (1.5) 10 (1.5)  
               
Lymphatic invasion       0.009      
 Negative 486 59 (46.8) 427 (59.3)   117 (58.5) 369 (57.1) 0.73
 Positive 360 67 (53.2) 293 (40.7)   83 (41.5) 277 (42.9)  
               
Venous invasion       0.102      
 Negative 702 98 (77.8) 604 (83.9)   162 (81.0) 540 (83.6) 0.399
 Positive 144 28 (22.2) 116 (16.1)   38 (19.0) 106 (16.4)  
               
Stage       0.024      
 I, II 634 84 (66.7) 550 (76.4)   141 (70.5) 493 (76.3) 0.101
 III, IV 212 42 (33.3) 170 (23.4)   59 (29.5) 153 (23.7)  

*s.d.=standard deviation.