Table 4. Decrease in LVEF ⩾10% on completion, 1 and 2 years after chemotherapy.

LVEF assessment	Standard AC	Accelerated AC	Standard EC	Accelerated EC
End of therapy	6 (14%)	3 (7%)	2 (11%)	2 (9%)
1 year after therapy	7 (17%)	3 (7%)	0	3 (13%)
2 years after therapy	6 (14%)	3 (7%)	3 (7%)	1 (4%)
Percentage with 2-year MUGA scans	71%	69%	58%	71%

Comparison ↓ LVEF ⩾10% between AC and EC regimens.

End of therapy, P=0.9.

One year post therapy, P=0.5.

Two years post therapy, P=1.0.

Comparison ↓ LVEF ⩾10% between standard and accelerated regimens.

End of therapy, P=0.7.

One year post therapy, P=0.8.

Two years post therapy, P=0.8.