Table 2.

ROI brain activation differences for negative minus positive anticipation. Increased activation for negative versus positive anticipation. The t-values are shown for the task effect (t-test versus the null hypothesis) and the group effect in these regions (with education covaried out).

						Task Effect		Group Effect
Volume	x	y	z	Side	Area	t-value	Sig	t-value	Sig
1024	−32	20	3	Left	Anterior Insula (Ia)	2.66	<0.01	0.47	NS
896	34	22	6	Right	Anterior Insula (Ia)	4.26	<0.001	0.32	NS
320	47	10	6	Right	Anterior/Middle Insula (Ia/Id)	3.91	<0.001	4.38	<0.05