. Author manuscript; available in PMC: 2009 Feb 2.

Published in final edited form as: Stat Med. 2008 Oct 15;27(23):4779–4789. doi: 10.1002/sim.3192

Table I.

Estimates of non-synonymous to synonymous substitution rates for plasma sequences, ω^P, CSF sequences, ω^C, and between plasma and CSF sequences, ω^B, under different evolutionary models.

Model	log L	Parameters	AIC_C	ω^P	ω^C	ω^B
Local	−6044.3	53	12194.6	n/a	n/a	1.9630
GA	−6045.2	37	12164.4	n/a	n/a	1.7
Within/between	−6057.3	34	12183.4	0.52	0.43	2.12
Global	−6065.6	33	12197.2	0.55	0.55	0.55

For the GA model where a GA determines the optimal number of rate classes and allocates rate classes to branches, the model averaged ω^B is given.