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. Author manuscript; available in PMC: 2009 Feb 2.
Published in final edited form as: J Med Genet. 2008 Oct 7;46(2):86–93. doi: 10.1136/jmg.2008.061580

Figure 3.

Figure 3

Gene expression analysis of 15q11-13 transcripts in post-mortem brain. A) Schematic representation of the genes analyzed in the critical region between BP2 and BP3 of 15q11-13. Arrows indicating the direction of transcription and the names of genes are shown to the left of the gray line, with the imprinting control region (ICR) shown as a filled circle at the 5′ end of SNRPN. B-K) Graphs summarizing quantitative RT-PCR measurements of 10 transcripts in the critical region normalized to GAPDH, with error bar representing +/- SEM. Fold changes relative to control expression are indicated above individual bars. Significant differences are indicated with * p < 0.01, ** p < 0.005, and *** p <0.0005. B and C are maternally expressed imprinted genes, D-G are paternally expressed imprinted genes, and H-K are nonimprinted biallelically expressed genes.