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. Author manuscript; available in PMC: 2010 Feb 20.
Published in final edited form as: Neurosci Lett. 2008 Dec 24;451(2):124–128. doi: 10.1016/j.neulet.2008.12.031

Fig. 4.

Fig. 4

SKF96365 inhibits SOCE in DRG neurons. (A-B) Representative traces show SOCE evoked by 5 μM CPA (applied at the times indicated by the horizontal bars) in PS1-D257A expressing cells (A) and in cells treated for 48 hrs with 100 μM DAPT (B) in the absence or presence of 10 μM SKF96365 (added 5 min prior to and during CPA treatment). (C) Bar graph summarizes the effects of 10 μM SKF96365 on the [Ca2+]i measured after 2000 s in CPA from untreated (control), PS1-D257A expressing and DAPT (48 hrs) treated cells (n≥5 for each group). *p<0.05, compared to vehicle-treated cells.